By Michael Le Page, Clare Wilson, Jessica Hamzelou, Sam Wong, Graham Lawton, Adam Vaughan, Conrad Quilty-Harper, Jason Arunn Murugesu and Layal Liverpool
Latest coronavirus quality arsenic of 1pm connected 29 November
Six omicron cases identified successful Scotland
Six cases of the omicron coronavirus variant person been identified successful Scotland, it was announced today. Some of the individuals affected person nary caller past of travel, and the root of their infections is not clear.
Contact tracers are trying to find the root of the microorganism successful Scotland. All adjacent contacts of suspected omicron cases are advised to self-isolate for 10 days – careless of vaccination status. The quality follows the confirmation of 3 different UK cases of the variant implicit the weekend successful Essex, Nottingham and London.
The omicron variant poses a “very high” planetary hazard of infection, the World Health Organisation (WHO) said connected Sunday.
The bureau warned that “there could beryllium aboriginal surges of covid-19, which could person terrible consequences”. Member states person been urged to accelerate vaccination programmes, peculiarly for radical who are susceptible and those who are not yet afloat vaccinated.
No deaths person been linked to the variant truthful far. Omicron was archetypal detected connected 23 November in South Africa, and caller cases person since been uncovered successful the UK, the Netherlands, Denmark and Australia.
Japan volition prohibition all overseas travellers entering the country from tomorrow successful airy of the emergence of the omicron variant. Israel has temporarily restricted the introduction of tourists arsenic of 28 November, and Morocco has implemented a two-week suspension of incoming rider flights arsenic of 29 November.
Essential accusation astir coronavirus
Where did coronavirus travel from? And different covid-19 questions answered
Covid-19 vaccines: Everything you request to cognize astir the starring shots
Long covid: Do I person it, however agelong volition it past and tin we dainty it?
What’s the fairest mode to stock covid-19 vaccines astir the world?
Covid-19: The communicative of a pandemic
What to read, ticker and perceive to astir coronavirus
New Scientist Weekly features updates and investigation connected the latest developments successful the covid-19 pandemic. Our podcast sees adept journalists from the mag sermon the biggest subject stories to deed the headlines each week – from exertion and space, to wellness and the environment.
The Jump is simply a BBC Radio 4 bid exploring however viruses tin transverse from animals into humans to origin pandemics. The archetypal occurrence examines the origins of the covid-19 pandemic.
Why Is Covid Killing People of Colour? is simply a BBC documentary, which investigates what the precocious covid-19 decease rates successful taste number patients uncover astir wellness inequality successful the UK.
Panorama: The Race for a Vaccine is simply a BBC documentary astir the wrong communicative of the improvement of the Oxford/AstraZeneca vaccine against covid-19.
Race Against the Virus: Hunt for a Vaccine is simply a Channel 4 documentary which tells the communicative of the coronavirus pandemic done the eyes of the scientists connected the frontline.
The New York Times is assessing the advancement successful improvement of imaginable cause treatments for covid-19, and ranking them for effectiveness and safety.
Humans of COVID-19 is simply a task highlighting the experiences of cardinal workers connected the frontline successful the combat against coronavirus successful the UK, done societal media.
Belly Mujinga: Searching for the Truth is simply a BBC Panorama probe of the decease of transport idiosyncratic Belly Mujinga from covid-19, pursuing reports she had been coughed and spat connected by a lawsuit astatine London’s Victoria Station.
Coronavirus, Explained connected Netflix is simply a abbreviated documentary bid examining the coronavirus pandemic, the efforts to combat it and ways to negociate its intelligence wellness toll.
COVID-19: The Pandemic that Never Should Have Happened, and How to Stop the Next One by Debora Mackenzie is astir however the pandemic happened and wherefore it volition hap again if we don’t bash things otherwise successful future.
The Rules of Contagion is astir the caller subject of contagion and the astonishing ways it shapes our lives and behaviour. The author, Adam Kucharski, is an epidemiologist astatine the London School of Hygiene and Tropical Medicine, UK, and successful the publication helium examines however diseases dispersed and wherefore they stop.
Unvaccinated individuals successful the US are overmuch much apt to dice from covid-19, CDC says
Unvaccinated radical successful the US are astatine a 14 times greater hazard of dying from covid-19 than those who are afloat vaccinated against coronavirus, according to data from September published by the US Centers for Disease Control and Prevention (CDC).
Unvaccinated individuals are besides astir six times arsenic apt to trial affirmative for the virus. While 196.4 cardinal radical successful the US are afloat vaccinated, and implicit 36 cardinal person received a booster dose, much than 47 cardinal adults and 12.4 cardinal teenagers are yet to beryllium afloat vaccinated, CDC manager Rochelle Wallensky told journalists astatine a White House property briefing connected Monday.
A akin representation is emerging successful the UK, wherever “covid-19 is nary longer a illness of the vaccinated”, according to Andrew Pollard, manager of the Oxford Vaccine Group astatine the University of Oxford. The “ongoing horror” of radical with covid-19 warring for enactment successful intensive attraction units successful hospitals crossed Britain “is present mostly restricted to unvaccinated people”, Pollard writes successful The Guardian.
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People successful England who are readying to caput to crowded enclosed areas are present being advised by the UK authorities to archetypal instrumentality lateral travel tests. People who are visiting individuals who are astatine a higher hazard of becoming earnestly sick with covid-19 whitethorn besides “wish to instrumentality a accelerated lateral travel test”, the government’s website states.
It is the archetypal clip authoritative guidance has encouraged members of the nationalist to instrumentality covid tests earlier taking portion successful definite activities.
The Pfizer/BioNTech covid-19 vaccine is 100 per cent effectual successful 12-to-15-year-olds astatine slightest 4 months aft a 2nd dose, according to proceedings results described successful a statement by the 2 companies.
The signifier 3 proceedings included 2228 volunteers. While 30 of the unvaccinated volunteers developed symptomatic cases of covid-19, nary specified cases developed among those who had been fixed 2 doses of the vaccine.
No superior information concerns were observed during a six-month travel up period, accidental the 2 companies. All 12-to-15-year-olds successful the UK are presently being offered a azygous dose of the vaccine.
Dashboard: Use our covid-19 dashboard to enactment up to day with deaths, cases and vaccination rates astir the world
Austria enters its 4th lockdown arsenic coronavirus cases surge
Austria went backmost into lockdown contiguous – becoming the archetypal European state to bash truthful successful effect to the latest surge successful covid-19 infections seen crossed the continent.
It is the country’s 4th nationalist lockdown since the pandemic began. People tin lone permission location for work, workout and market shopping. Non-essential shops, restaurants, bars and cinemas volition beryllium closed until 12 December – though officials accidental lockdown measures volition beryllium reassessed successful 10 days’ time.
Austria is presently reporting 173,500 progressive coronavirus infections. 1,102 coronavirus cases per 100,000 residents were recorded connected 20 November. The UK, by comparison, is presently reporting a fig of 418 cases per 100,000 radical successful the 7 days up to 16 November.
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Water cannons and teardrop state were deployed against radical protesting covid restrictions successful Brussels connected Sunday.
Around 35,000 individuals gathered to protestation caller covid rules, which see the mandatory wearing of look coverings successful nationalist spaces and moving from home. Some protesters threw objects astatine police, who past utilized h2o cannons and teardrop state to disperse the crowds.
Restrictions protests person besides occured successful Austria, the Netherlands, Italy and Switzerland.
Time is moving retired to forestall a “dangerous” surge of coronavirus infections successful the US, Anthony Fauci, manager of the US National Institute of Allergy and Infectious Diseases (NIAID) said yesterday.
Coronavirus cases successful the US are rising again, with caller cases approaching 100,000 per day. Millions of radical successful the US thin to question to sojourn household during the Thanksgiving holiday, which this twelvemonth falls connected 25 November. This could pb to a further surge successful cases, Fauci warns.
All US adults that are eligible for a vaccine booster should get one, Fauci told CNN connected Sunday. “As we’re getting into the vacation season, you privation to beryllium afloat protected,” helium said. “Bottom line… get boosted.”
Review of studies reinforces the effectiveness of look coverings, handwashing and societal distancing
Mask wearing is 1 of the astir effectual nationalist wellness measures for preventing covid-19, and is associated with a 53 per cent simplification successful the incidence of the disease, according to a reappraisal of published research.
Stella Talic astatine Monash University successful Australia and her colleagues carried retired a meta-analysis utilizing information from 72 studies to measure the effectiveness of non-pharmaceutical interventions – measures that don’t impact drugs – astatine containing the virus.
Handwashing was besides estimated to beryllium associated with a 53 per cent simplification successful covid-19 incidence, but this effect was not statistically important due to the fact that lone a tiny fig of studies connected it were included. Physical distancing was associated with a 25 per cent simplification successful covid-19 incidence.
“It is apt that further power of the covid-19 pandemic depends not lone connected precocious vaccination sum and its effectiveness but besides connected ongoing adherence to effectual and sustainable nationalist wellness measures,” Talic and her colleagues constitute successful the British Medical Journal.
We updated the supra communicative connected 25 November to clarify that the reappraisal recovered associations betwixt these measures and reduced covid-19 incidence.
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Children aged 12 to 17 who person had a covid-19 corruption should not get a vaccine until 12 weeks later, according to new guidance successful the UK. This could assistance to trim the “very, precise small” hazard of bosom inflammation aft vaccination, experts from the UK Health Security Agency said. The existent lawsuit rates of myocarditis aft vaccination among under-18s are suspected to beryllium astir 9 per cardinal vaccinations, and cases person been “relatively mild”, officials said. Research suggests that myocarditis is overmuch much apt to occur aft a coronavirus corruption than aft vaccination. For older radical and for anyone who is precocious hazard and aged 12 oregon over, the existent proposal is that they should hold 4 weeks betwixt covid corruption and having a dose of vaccine.
A 4th question of the pandemic is hitting Germany “with afloat force”, chancellor Angela Merkel has said up of a situation gathering with determination leaders. Authorities are considering caller measures to regenerate nationwide rules that expire astatine the extremity of the month. Lothar Wieler, the manager of the Robert Koch Institute, a German authorities agency, said the state is heading towards a superior emergency, with hospitals already struggling to find abstraction for patients. “We are going to person a truly unspeakable Christmas if we don’t instrumentality countermeasures now.”
AstraZeneca has reported that its preventative antibody cause AZD7442 offered 83 per cent protection against covid-19 implicit six months successful a objective trial. The injected therapy could supply an alternate enactment for preventing unwellness successful radical who bash not equine a bully immune effect to vaccines.
A 5th of cyberattacks successful UK targeted vaccine firms oregon wellness organisations
Hackers targeted labs this twelvemonth that were crucial to the UK’s pandemic response, according to the National Cyber Security Centre.
The watchdog said that it handled a grounds 777 cyberattack incidents betwixt August 2020 and September 2021. A 5th of these targeted firms were linked to vaccines and the wellness sector.
It besides said that it helped the University of Oxford’s AstraZeneca vaccine researchers support themselves against an attempted ransomware onslaught that could person had large ramifications for the UK’s pandemic response.
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Pfizer has allowed cheaper versions of its prospective antiviral covid-19 pill to beryllium made successful poorer countries – granting entree to hundreds of millions of people.
The pharmaceutical elephantine says it volition let generic copies of Paxlovid to beryllium made successful 95 debased and middle-income countries, covering 53 per cent of the population.
Ireland’s bars, restaurants and nightclubs volition person a midnight curfew from Thursday to curb coronavirus infections. Ireland’s premier minister, Micheal Martin, besides said that everyone should enactment from location unless it is “absolutely necessary” not to.
Strict covid rules came into unit successful Beijing, China, contiguous as the state gears up for the Winter Olympics adjacent year. Anyone visiting the metropolis indispensable amusement a antagonistic covid trial from the past 48 hours.
995 covid-related deaths were recorded successful the week ending 5 November
The week ending 5 November saw the highest fig of covid-related deaths successful England and Wales since March. The UK Office for National Statistics reported 995 covid-related deaths successful that week, representing 8.6 per cent of each deaths. It is the largest fig since the week ending 12 March, and a 16 per cent emergence connected the fig of covid-related deaths from the erstwhile week.
In total, 168,600 decease certificates person mentioned covid-19 successful the UK since the pandemic began. The highest fig connected a azygous time was 1,484 connected 19 January 2021.
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Antidepressant usage is linked to a little hazard of dying from covid-19, according to an investigation of aesculapian records successful the US. Researchers successful California assessed a database of astir 83,500 radical diagnosed with covid-19. The 3401 individuals who were taking fluoxetine, a selective serotonin reuptake inhibitor (SSRI), appeared to beryllium much apt to past the infection.
“We can’t archer if the drugs are causing these effects, but the statistical investigation is showing important association,” says Marina Sirota astatine the University of California, San Francisco.
Travel restrictions successful India person been removed for afloat vaccinated tourists for the archetypal clip since the pandemic began. Many travellers indispensable besides trial antagonistic for the microorganism wrong 72 hours of their flight, though this won’t use to those visiting from countries that person an statement with India successful place, specified arsenic those from the US, UK and immoderate different European countries.
Amazon has been fined $500,000 by California officials for failing to “adequately notify” workers astir caller covid-19 cases successful the workplace.
Amazon employs astir 150,000 radical successful California, astir of whom enactment successful the company’s mammoth warehouses. California authorities requires companies to notify workers astir caller coronavirus cases among employees.
16 and 17-year-olds acceptable to beryllium offered 2nd doses of covid-19 vaccines
The UK’s covid-19 vaccine booster programme volition beryllium extended to see each 40 to 49-year-olds, pursuing a proposal from the government’s vaccination advisers. The Joint Committee connected Vaccination and Immunisation (JCVI) has advised that each adults implicit the property of 40 should beryllium offered a booster, six months aft their 2nd dose.
It has besides advised 16 and 17-year-olds to travel guardant for a 2nd dose of the Pfizer/BioNTech jab, which should beryllium fixed astatine slightest 12 weeks aft the first.
Until now, boosters person been offered to radical implicit 50 and younger radical who are clinically vulnerable, and 12.6 cardinal radical person had a 3rd covid-19 jab truthful far. The JCVI said radical should beryllium offered the Pfizer oregon Moderna jab arsenic a booster, irrespective of which vaccine they had initially.
Sajid Javid, the wellness secretary, said the proposal has been accepted successful England and NHS England has been instructed to instrumentality it arsenic soon arsenic possible. The Scottish authorities besides said it would widen the booster programme.
The announcement comes arsenic a caller survey from the UK Health Security Agency finds that booster vaccines trim the hazard of symptomatic covid-19 by astatine slightest 93 per cent successful adults implicit 50. Protection against much terrible illness and decease is expected to beryllium adjacent higher.
“Booster vaccine doses successful much susceptible adults, and 2nd vaccine doses successful 16 to 17-year-olds are important ways to summation our extortion against covid-19 corruption and terrible disease,” Wei Shen Lim, seat of covid-19 immunisation for the JCVI, said successful a statement. “These vaccinations volition besides assistance widen our extortion into 2022.”
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Austria has ordered a nationwide lockdown for anyone implicit 12 who is not afloat vaccinated against covid-19. This radical – astir 2 cardinal radical – volition lone beryllium allowed to permission location for constricted reasons, including going to enactment oregon buying for essentials. Around 65 per cent of the colonisation is afloat vaccinated, 1 of the lowest rates successful Europe.
A caller covid-19 vaccine that works via T-cells alternatively than antibodies is astir to participate quality trials. Existing covid-19 vaccines chiefly purpose to make immunity based connected antibodies, proteins that instrumentality to the microorganism and halt it from infecting cells. T-cells are different portion of the immune strategy that find and destruct infected cells, and they are thought to connection longer-lasting immunity. The experimental vaccine is administered via a tegument patch. Emergex, the institution that developed it, has been fixed a greenish airy to transportation retired an archetypal proceedings involving 26 radical successful Lausanne, Switzerland, The Guardian reports.
Latest connected coronavirus from New Scientist
Covid-19 successful chaotic animals: Recent studies suggest that SARS-CoV2, the microorganism that causes covid-19, is rife among white-tailed cervid successful North America. Animal reservoirs of the virus summation the chances of perchance unsafe caller variants emerging and crossing backmost into humans.
Covid-19 cases rising successful Europe but unchangeable oregon falling successful remainder of the world
Coronavirus deaths successful Europe jumped by 10 per cent successful the week to 7 November, according to the latest epidemiological update from the World Health Organization (WHO). New cases of covid-19 accrued by 7 per cent successful Europe, portion different regions saw lawsuit numbers stay unchangeable oregon decline. The planetary fig of recorded covid-19 deaths successful the week was 48,000, a 4 per cent alteration from the erstwhile week.
Europe had the highest incidence of confirmed cases, with 208.9 cases per 100,000 population, up of the Americas which had 68.8 caller cases per 100,000.
Hans Kluge, the WHO manager for Europe, said the portion was “back astatine the epicentre of the pandemic” and could spot different 500,000 deaths by February if much actions aren’t taken to bounds the dispersed of the virus, Euronews reports.
The countries with the highest numbers of caller cases are the US, Russia, UK, Turkey and Germany. In Russia, implicit 1000 deaths person been reported each time since precocious October. Some hospitals successful Germany are reportedly incapable to admit caller patients due to the fact that of the precocious numbers of radical needing attraction for covid-19.
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Tens of thousands of attraction location unit successful England who person not had 2 coronavirus vaccine doses volition beryllium incapable to legally enactment successful attraction homes from contiguous arsenic a mandatory jab argumentation comes into effect. Staff moving successful registered attraction homes successful England indispensable person had some jabs to proceed successful their relation unless they are medically exempt. Official figures due aboriginal contiguous are expected to amusement that much than 50,000 existent unit successful attraction homes person not been recorded arsenic having had some doses arsenic of 7 November, 4 days earlier the deadline. Several 1000 of these are understood to person self-certified arsenic medically exempt oregon to person applied for ceremonial proof.
A survey showing that immoderate radical whitethorn person had pre-existing immunity to the SARS-CoV-2 virus during the archetypal question of the pandemic has raised hopes that a cosmopolitan coronavirus vaccine could beryllium developed. The probe recovered that immoderate healthcare workers successful the UK who were regularly tested encountered the covid-19 microorganism but ne'er became afloat infected with it oregon developed covid-19 antibodies. These radical are thought to person had an immune representation successful their T cells due to the fact that of vulnerability to other coronaviruses that origin seasonal colds. Read New Scientist’s communicative to find retired more.
The fig of antibiotic prescriptions successful England during the archetypal twelvemonth of the covid-19 pandemic dropped by 17 per cent compared with the erstwhile year, according to investigation by the foundation Antibiotic Research UK. Prescriptions successful the wintertime were lone 4 per cent higher than successful the summer, compared with a 21 per cent seasonal quality earlier the pandemic. The inclination whitethorn beryllium owed successful portion to little corruption transmission during lockdowns.
France follows Israel successful starting to marque booster shots a request for vaccine passes for the over-65s
French radical aged implicit 65 volition person to person a 3rd dose of the coronavirus vaccine to beryllium they person been fully vaccinated connected their wellness passes from mid-December. The passes amusement if a idiosyncratic has been immunised, has precocious recovered from corruption oregon has precocious had a antagonistic test. In France they are needed for galore communal activities including going to restaurants and bars, libraries, the gym and for long-distance bid and level journeys.
President Emmanuel Macron besides said yesterday that boosters would beryllium disposable for radical betwixt the ages of 50 and 65 from adjacent month, and that usage of wellness passes would increase. Although corruption rates successful France are little than successful immoderate different European countries specified arsenic Germany, they are rising. Macron said a “fifth wave” of covid-19 had arrived successful Europe. “We are not yet finished with the pandemic.”
Israel has besides made boosters six months aft a 2nd dose a information for its digital vaccine certificates. Meanwhile successful Wales, a request for covid passes showing treble vaccination oregon a caller antagonistic covid-19 trial volition beryllium extended to theatres, concerts and museums from Monday.
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An antiviral medicine that tin beryllium taken astatine location and cuts hospitalisations and deaths from covid-19 by astir 90 per cent could beryllium disposable by very aboriginal adjacent year, the caput of Pfizer UK has said. The pills, called Paxlovid, are taken doubly regular for 5 days, by radical who are astatine hazard of processing terrible disease.
Unvaccinated radical successful Singapore could look a hefty infirmary measure if they request attraction for covid-19 from adjacent year. The authorities has said it volition nary longer wage aesculapian bills for radical with covid-19 who are “unvaccinated by choice”.
Frontline NHS unit volition person to person some doses of vaccine by spring
The UK authorities is expected to denote mandatory covid-19 vaccinations for frontline National Health Service (NHS) unit successful England, with a deadline of adjacent outpouring for some doses. The Department of Health said it was not commenting connected speculation astir the timing of the announcement, which the BBC said would beryllium aboriginal connected Tuesday. However, NHS officials said they expect the determination to happen. The measurement is expected to impact thousands of unvaccinated unit moving successful the wellness service.
Care location workers successful England person already been told they indispensable beryllium afloat vaccinated by this Thursday. According to NHS figures, tens of thousands of attraction location unit were not recorded arsenic having been treble jabbed yet arsenic of 31 October.
NHS Providers main enforcement Chris Hopson said determination are betwixt 80,000 and 100,000 NHS workers successful England who are unvaccinated. “If we get it right, actually, it could beryllium rather a utile spur successful immoderate senses to thrust the take-up up, but the spot that we conscionable request to beryllium cautious of is avoiding scapegoating people,” helium told BBC Radio 4’s Today programme.
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More than 11,000 radical who died of covid-19 successful England are thought to person caught the microorganism successful a National Health Service hospital, The Telegraph has reported. The fig was compiled from information collected by NHS trusts utilizing Freedom of Information laws. The trusts besides reported implicit 40,000 probable oregon definite hospital-acquired covid-19 infections. Some trusts refused to disclose their data, suggesting the existent numbers are adjacent higher.
France’s nationalist wellness authorization has recommended that radical nether 30 should beryllium fixed the Pfizer/BioNTech coronavirus vaccine successful penchant to the Moderna vaccine, due to the fact that of a uncommon broadside effect. The hazard of myocarditis, a bosom condition, successful this property radical is astir 5 times little successful radical who person the Pfizer jab than Moderna, the Haute Autorité de Santé said.
Eligible radical who bash not instrumentality up boosters could look question restrictions
More than 10 cardinal radical person had covid-19 booster vaccines oregon 3rd doses successful the UK, arsenic politicians urged others who are eligible to get their jabs.
People implicit 50 and those astir astatine hazard from covid-19 are among those eligible for a covid vaccine booster shot. From today, the NHS booking strategy volition let radical to publication a booster assignment 5 months aft their 2nd dose.
The latest figures amusement that 10,062,704 radical successful the UK person received a booster oregon 3rd dose, with 409,663 receiving 1 connected Saturday. But astir 30 per cent of over-80s and 40 per cent of over-50s successful England are yet to person a booster, the Department of Health and Social Care said.
On Sunday, the UK wellness caput Sajid Javid urged eligible radical to get the vaccine, saying it would assistance the state “avoid a instrumentality to restrictions and bask Christmas”.
According to media reports, ministers are considering changing question rules truthful that those who are eligible but garbage a 3rd dose look stricter quarantine and investigating rules. Official guidance was updated earlier this period to accidental the Government “is reviewing the implications and requirements of boosters for planetary question certification” and “looking astatine whether and however booster vaccinations could beryllium included successful the NHS Covid Pass for travel”.
Deaths from covid-19 are progressively occurring successful vaccinated people, due to the fact that of immunity waning implicit time, said Susan Hopkins, main aesculapian advisor astatine the UK Health Security Agency. “It is peculiarly the older property groups, truthful the over-70s successful particular, but besides those who are clinically vulnerable, highly vulnerable, and person underlying aesculapian conditions,” she said.
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The UK volition statesman rolling out the covid-19 antiviral cause molnupiravir successful a objective proceedings aboriginal this month, Susan Hopkins astatine the UK Health Security Agency has said. Molnupiravir, developed by Merck and Ridgeback Biotherapeutics, was approved by the UK medicines regulator past week. Trials person shown that it halves the hazard of unvaccinated radical needing infirmary attraction oregon dying, and further trials are needed to spot however it works successful the vaccinated population, Hopkins said.
Restrictions connected travelling to the US from 33 countries have been lifted today. The ban, covering the UK, overmuch of Europe, China and India, has been successful spot since aboriginal 2020. Proof of vaccination and a caller antagonistic covid-19 trial are present required to participate the US.
First antiviral approved for usage by susceptible radical astatine home
A caller antiviral therapy cuts the hazard of being hospitalised oregon dying from covid-19 by astir 90 per cent. The treatment, called Paxlovid, is fixed doubly regular for 5 days to radical extracurricular of infirmary who are astatine hazard of terrible illness.
Paxlovid, made by US steadfast Pfizer, is simply a operation of 2 drugs; a compound presently called PF-07321332, which blocks enactment of an enzyme that the coronavirus needs to replicate. The 2nd cause is called ritonavir; developed arsenic a attraction for HIV, it helps dilatory the breakdown of PF-07321332.
In a placebo-controlled proceedings of 1219 radical from each implicit the world, 0.8 per cent of radical who received Paxlovid wrong 3 days of a affirmative covid-19 trial required infirmary treatment, compared with 7 per cent of radical who received a placebo. The equivalent figures were 1 and 6.7 per cent for those who got attraction wrong 5 days. The results person not yet been afloat published, but were announced contiguous successful a press merchandise from Pfizer.
Meanwhile, different antiviral called molnupiravir was approved yesterday successful the UK. This medicine is besides fixed doubly regular to radical who are astatine hazard of terrible unwellness but person not been hospitalised. Trials showed it halves the hazard of radical needing infirmary attraction oregon dying.
Molnupiravir should beryllium taken arsenic soon arsenic imaginable aft a affirmative covid-19 test, oregon astatine slightest wrong 5 days. It works by causing mutations arsenic the microorganism duplicates its familial material, stopping it from multiplying wrong cells. The UK Medicines and Healthcare products Regulatory Agency (MHRA) has authorised its usage for radical with at slightest 1 hazard origin for terrible infection, including being 60 oregon older, having diabetes, bosom illness oregon obesity.
“We are moving astatine gait to deploy molnupiravir to patients done a nationalist survey arsenic soon arsenic possible,” Health and Social Care Secretary Sajid Javid said successful a statement. Penny Ward astatine King’s College London said successful a connection that the authorities whitethorn privation to measure its effectiveness successful radical who are vaccinated, arsenic the trials truthful acold person been successful unvaccinated people.
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Opening windows for 10 minutes each hr volition assistance trim the hazard of catching the coronavirus indoors, radical successful England are being told successful a public accusation run launching today. The cardinal connection of the campaign, moving connected vigor stations and successful the press, is to “Stop coronavirus hanging around”, by improving ventilation.
Europe is erstwhile again astatine the “epicentre” of the covid-19 pandemic, acknowledgment to countries relaxing prevention measures and uneven vaccine coverage, the World Health Organization has said. Hans Kluge, the WHO’s Europe director, said yesterday that each European countries were either facing “a existent menace of covid-19 resurgence oregon already warring it”.
The pandemic has led to the nonaccomplishment of astatine slightest 28 cardinal years of life
The pandemic led to the nonaccomplishment of 28 cardinal years of beingness globally successful 2020 – though this fig is apt to beryllium a terrible underestimate arsenic it lone looked astatine 37 countries.
Researchers astatine the University of Oxford calculated however galore years of beingness had been mislaid owed to coronavirus successful 37 countries, including Russia, the US and Italy. They did this by analysing excess deaths successful each nation, the ages of those who died, and each country’s mean beingness expectancy.
They calculated that much than 28 cardinal years of beingness had been mislaid crossed 31 of the countries they analysed. Six countries, including New Zealand, Denmark and South Korea, did not spot an summation successful nonaccomplishment of years of beingness arsenic a effect of the pandemic. However globally, the full mislaid years of beingness owed to the pandemic volition beryllium overmuch higher, and the team’s investigation did not see galore Asian, African oregon South American countries owed to a deficiency of data.
The researchers besides looked astatine beingness expectancy declines successful each state for 2020. The biggest falls were seen successful Russia, the US and Bulgaria. In England and Wales, antheral beingness expectancy dropped by 1.2 years, portion pistillate beingness expectancy dropped by 0.8-years.
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Coronavirus infections astir doubled successful over-65s betwixt September and October successful England. In the latest survey by Imperial College London, astir 0.8 per cent of 65 to 74-year-olds tested affirmative for coronavirus, portion 0.67 per cent of over-75s had covid-19 successful betwixt 19 and 29 October. But school-children proceed to beryllium astir astatine hazard from corruption with astir six per cent of five-to-17-year-olds investigating affirmative for the virus.
India’s home-grown vaccine, Covaxin, has been approved for exigency use by the World Health Organisation. It is the seventh jab to beryllium approved by the intergovernmental body. More than 105 cardinal doses of the vaccine person been administered to radical successful India truthful far.
Covid-19 jabs for elementary-school-aged children fixed last sign-off
The US is gearing up to connection covid-19 vaccines to 5-to-11-year-olds this week, aft the Pfizer/BioNTech jab passed its last hurdle of support by the country’s Centers for Disease Control and Prevention yesterday. The vaccine has been approved for this property radical astatine 1 3rd of the dose utilized for adults and teenagers. The child-sized doses volition beryllium packaged successful bottles with orangish lids to debar mix-ups.
Vaccines could commencement being offered this week, but it volition beryllium adjacent week earlier roll-out would beryllium “fully up and running”, Jeff Zients of the White House said connected Monday. There would beryllium “millions much doses packed, shipped and delivered and thousands of further sites coming online each day”, helium said. In the UK, the Medicines and Healthcare products Regulatory Agency is inactive reviewing the children’s vaccine. Yesterday Pfizer reported that its net and sales more than doubled successful the past quarter, chiefly acknowledgment to its covid-19 vaccines.
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A subordinate of the UK government’s Scientific Advisory Group for Emergencies (SAGE) stepped down astatine the extremity of October. Sir Jeremy Farrar, caput of the Wellcome wellness charity, had been advocating for much restrictions, specified arsenic look disguise wearing, to beryllium brought successful owed to the UK’s existent precocious level of coronavirus infections, according to Sky News. “The precocious levels of transmission seen successful the UK stay concerning,” helium said. “My absorption present indispensable beryllium connected our enactment astatine Wellcome. This includes supporting the planetary probe effort to extremity the pandemic.”
The Netherlands has reintroduced covid restrictions, 1 of the archetypal occidental European countries to bash truthful aft measures were relaxed implicit summer. They volition see caller requirements to deterioration look masks, asking radical to enactment from location fractional the week wherever imaginable and extending the usage of covid passes to edifice terraces and museums. According to information from Johns Hopkins University, 7727 caller covid-19 cases were reported successful the Netherlands connected 2 November, compared with 33,546 successful the UK.
Self-isolation compliance falls successful 35 to 54-year-olds
One successful 4 radical betwixt the ages of 35 and 54 are failing to self-isolate for a afloat 10 days aft investigating affirmative for coronavirus, according to the Office for National Statistics.
The figures are based connected a survey of 881 radical successful England conducted successful precocious September and aboriginal October. The researchers recovered that lone 75 per cent of participants isolated for 10 days aft a affirmative covid-19 test. It is simply a large driblet from the 86 per cent who reported afloat compliance successful July.
The other inclination was seen successful radical aged betwixt 18 and 34, with 82 per cent reporting afloat compliance successful the latest survey arsenic opposed to 75 per cent successful July.
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Around 9000 New York City nationalist workers were enactment connected unpaid permission connected Monday for not being vaccinated. The city’s vaccine mandate for nationalist assemblage workers came into effect yesterday. One successful 4 firefighters successful the metropolis are inactive not vaccinated, portion 1 successful six constabulary unit are besides unjabbed.
Indonesia has go the archetypal state successful the satellite to springiness exigency authorisation for the Novavax vaccine. Studies person shown that it is astir 90 per cent effectual against symptomatic covid-19.
Disneyland Shanghai successful China has been unopen for astatine slightest 2 days owed to a azygous visitant investigating affirmative for coronavirus. The determination comes arsenic the state aims to deed zero coronavirus infections by the clip it hosts the Winter Olympics aboriginal adjacent year.
Global recorded covid-19 decease toll hits 5 million
The fig of full recorded deaths from covid-19 worldwide has deed 5 million, little than 2 years since the pandemic begun.
Around 7000 radical astir the globe are dying from the microorganism each day, according to figures compiled by Johns Hopkins University in the US.
But the existent fig is apt to beryllium much than treble that. Analysis by The Economist suggests the toll is astir apt person to 16.7 cardinal deaths – aft taking into relationship those who died from the illness without knowing they had contracted the microorganism and those who could not beryllium treated for different illnesses due to the fact that hospitals were overwhelmed with covid-19 patients.
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Booster jabs are present disposable astatine walk-in sites successful England for those who received their 2nd dose astatine slightest six months agone and who conscionable definite eligibility criteria, specified arsenic being aged 50 oregon over, oregon being a frontline wellness oregon societal worker. It means implicit 30 cardinal radical who conscionable these criteria volition nary longer person to publication an assignment to get a booster shot. More than six cardinal person had a booster jab oregon a 3rd dose truthful far, according to NHS England.
Activists from processing countries person been excluded from COP26 owed successful portion to planetary vaccine inequality, climate alteration activists person claimed.Lidy Nacpil, of the Asian People’s Movement connected Debt and Development, who is based successful the Philippines, told The Guardian: “The challenges and complications related to vaccines, visas and quarantine requirements that the UK failed to adequately code are the main reasons wherefore we volition not beryllium astatine COP26.”
See erstwhile updates from September to October 2021, July to September 2021, June to July 2021, May 2021, April-March 2021, February 2021, January 2021, November/December 2020, and March to November 2020.
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